Consumer medicine information

1. Why am I given CEFTAZIDIME VIATRIS?

CEFTAZIDIME VIATRIS contains the active ingredient ceftazidime (as pentahydrate). CEFTAZIDIME VIATRIS is used to treat a wide range of infections caused by bacteria.
For more information, see Section 1. Why am I given CEFTAZIDIME VIATRIS? in the full CMI.

2. What should I know before I am given CEFTAZIDIME VIATRIS?

You must not be given CEFTAZIDIME VIATRIS if you have ever had an allergic reaction to medicines containing cephalosporins or penicillins, or any of the ingredients listed at the end of the CMI.
Talk to your doctor if you have any other medical conditions, take any other medicines, or are pregnant or plan to become pregnant or are breastfeeding.
For more information, see Section 2. What should I know before I am given CEFTAZIDIME VIATRIS? in the full CMI.

3. What if I am taking other medicines?

Some medicines and CEFTAZIDIME VIATRIS may interfere with each other.
A list of these medicines is in Section 3. What if I am taking other medicines? in the full CMI.

4. How CEFTAZIDIME VIATRIS is given?

CEFTAZIDIME VIATRIS will always be prepared and given to you by a doctor or another healthcare professional. CEFTAZIDIME VIATRIS will be injected deep into muscle tissue or into a vein. When it is injected into a vein it may be given directly or through a 'drip'.
More instructions can be found in Section 4. How CEFTAZIDIME VIATRIS is given? in the full CMI.

5. What should I know while I am given CEFTAZIDIME VIATRIS?

6. Are there any side effects?

Like other medicines, CEFTAZIDIME VIATRIS may have unwanted side effects in some people. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects.
For more information, including what to do if you have any side effects, see Section 6. Are there any side effects? in the full CMI.

1 Name of Medicine

Ceftazidime pentahydrate.

2 Qualitative and Quantitative Composition

Ceftazidime Viatris is supplied in vials containing 1 g and 2 g of ceftazidime (as pentahydrate). 116.4 mg ceftazidime pentahydrate is equivalent to 100 mg ceftazidime free acid.
For the full list of excipients, see Section 6.1 List of Excipients.

3 Pharmaceutical Form

Ceftazidime Viatris is a powder for injection and is a white or almost white, crystalline powder.
On the addition of water for injections, Ceftazidime Viatris dissolves with effervescence to produce a solution for injection.
Ceftazidime Viatris containing 1 g ceftazidime (as pentahydrate) is used for IV injection or IM injection.
Ceftazidime Viatris containing 2 g ceftazidime (as pentahydrate) is used for IV injection or IV infusion.

4 Clinical Particulars

4.9 Overdose

Overdosage can lead to neurological sequelae including encephalopathy, convulsions and coma. Ceftazidime can be removed by haemodialysis.
For information on the management of overdose, contact the Poisons Information Centre on 13 11 26 (Australia).

5 Pharmacological Properties

5.3 Preclinical Safety Data

Genotoxicity. No data available.
Carcinogenicity. No data available.

6 Pharmaceutical Particulars

6.7 Physicochemical Properties

Ceftazidime pentahydrate is slightly soluble in water and in methanol, practically insoluble in acetone and in alcohol. It dissolves in acid and alkali solutions.
Chemical structure. Chemical name: (6R,7R)-7-[[(Z)-2-(2-aminothiazol-4-yl)-2- [(1-carboxy-1-methylethoxy)imino] acetyl] amino]8-oxo-3-[(1-pyridinio)methyl]- 5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate pentahydrate.
Structural formula:
https://stagingapi.mims.com/au/public/v2/images/fullchemgif/CSCEFPEN.gif Molecular formula: C₂₂H₂₂N₆O₇S₂.5H₂O.
Molecular weight: 637.
CAS number. 78439-06-2.

7 Medicine Schedule (Poisons Standard)

S4 - Prescription Only Medicine.

Summary Table of Changes

https://stagingapi.mims.com/au/public/v2/images/fulltablegif/CEFVIAST.gif