Consumer medicine information

1. Why am I using Celestone M?

Celestone M contains the active ingredient betamethasone valerate. Celestone M is used on the skin to relieve the redness, swelling, itching and discomfort of many skin problems.
For more information, see Section 1. Why am I using Celestone M? in the full CMI.

2. What should I know before I use Celestone M?

Do not use if you have ever had an allergic reaction to betamethasone valerate or any of the ingredients listed at the end of the CMI.
Talk to your doctor if you have any other medical conditions, take any other medicines, or are pregnant or plan to become pregnant or are breastfeeding.
For more information, see Section 2. What should I know before I use Celestone M? in the full CMI.

3. What if I am taking other medicines?

Some medicines may interfere with Celestone M and affect how it works.
More information can be found in Section 3. What if I am taking other medicines? in the full CMI.

4. How do I use Celestone M?

• Apply a thin film of Celestone M Cream to the affected skin two to three times daily. Massage gently until it disappears

5. What should I know while using Celestone M?

6. Are there any side effects?

Local, skin-related side effects such as burning, itching, irritation, infection or dryness, acne, skin thinning and discolouration have been reported with the use of topical corticosteroids, especially under occlusive dressings.
For more information, including what to do if you have any side effects, see Section 6. Are there any side effects? in the full CMI.

1 Name of Medicine

Betamethasone valerate.

2 Qualitative and Quantitative Composition

Celestone-M Cream contains betamethasone valerate equivalent to betamethasone 0.2 mg/g.
Excipients with known effect. Celestone-M Cream contains cetostearyl alcohol and chlorocresol.
For the full list of excipients, see Section 6.1 List of Excipients.

3 Pharmaceutical Form

Cream.

4 Clinical Particulars

4.9 Overdose

Symptoms. Excessive prolonged use of topical corticosteroids can suppress pituitary adrenal function resulting in secondary adrenal insufficiency, and produce manifestations of hypercorticism, including Cushing's disease.
Treatment. Appropriate symptomatic treatment is indicated. Acute hypercorticoid symptoms are virtually reversible. Treat electrolyte imbalance, if necessary. In cases of chronic toxicity, slow withdrawal of corticosteroids is advised.
For information on the management of overdose, contact the Poison Information Centre on 131126 (Australia).

5 Pharmacological Properties

5.3 Preclinical Safety Data

Genotoxicity. No data available.
Carcinogenicity. No data available.

6 Pharmaceutical Particulars

6.7 Physicochemical Properties

Chemical structure.
https://stagingapi.mims.com/au/public/v2/images/fullchemgif/CSBETVAL.gif Betamethasone valerate is 9-fluoro-11β, 21-dihydroxy-16β-methyl-3, 20-dioxopregna-1,4-dien-17-yl pentanoate. The empirical formula is C₂₇H₃₇FO₆. MW = 476.6.
CAS number. CAS Registry number is 2152-44-5.

7 Medicine Schedule (Poisons Standard)

Prescription Only Medicine (Schedule 4).

Summary Table of Changes

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