Consumer medicine information

1. Why am I using Intralipid?

Intralipid contains the active ingredient soya oil. Intralipid is a supplement to parenteral nutrition, which provides your body with energy and fatty acids. It is usually given together with carbohydrates, amino acids, salts, trace elements and vitamins to provide a complete intravenous diet.
For more information, see Section 1. Why am I using Intralipid? in the full CMI.

2. What should I know before I use Intralipid?

• Do not use if you have ever had an allergic reaction to soy, eggs, peanuts or any of the ingredients listed at the end of the CMI. Tell your doctor if you have an inability to break down fats.

3. What if I am taking other medicines?

Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop.
Some medicines may interfere with Intralipid and affect how it works.
A list of these medicines is in Section 3. What if I am taking other medicines? in the full CMI.

4. How do I use Intralipid?

• The dose of Intralipid which you will require will be determined by your doctor or pharmacist. Your doctor will supervise your treatment with Intralipid.

5. What should I know while using Intralipid?

6. Are there any side effects?

Less serious side effects have been reported during post-marketing, including rise in body temperature, nausea, vomiting, shivering, chills, skin rash, hives, rapid breathing, shortness of breath, headache, effects on blood pressure, slight pressure over the eyes, abdominal pain, flushing and dizziness. If you get any adverse effects, talk to your doctor or nurse.
For more information, including what to do if you have any side effects, see Section 6. Are there any side effects? in the full CMI.

1 Name of Medicine

Soya oil.

2 Qualitative and Quantitative Composition

Sterile fat emulsions for intravenous infusion containing (see Table 1):
https://stagingapi.mims.com/au/public/v2/images/fulltablegif/INTRAL01.gif For the full list of excipients, see Section 6.1 List of Excipients.

3 Pharmaceutical Form

Intravenous infusion for injection.
A milky white liquid.

4 Clinical Particulars

4.9 Overdose

Please see Section 4.8 Adverse Effects (Undesirable Effects), Fat overload syndrome.
For information on the management of overdose, contact the Poison Information Centre on 131126 (Australia) or 0800 764 766 (New Zealand).

5 Pharmacological Properties

5.3 Preclinical Safety Data

Genotoxicity. No studies have been performed.
Carcinogenicity. No studies have been performed.

6 Pharmaceutical Particulars

6.7 Physicochemical Properties

Chemical structure. Soya oil is a mixture of triglycerides, i.e. triacylglycerols. The triglycerides, triacylglycerols, are fatty acid triesters of glycerol (propane-1, 2, 3-triol). The main fatty acids are linoleic acid (C18:2), oleic acid (C18:1) and palmitic acid (C16:0). The number of double bonds in the different fatty acids can vary from zero (saturated) to three (unsaturated). As with most vegetable oils, the saturated acids are preferably esterified in sn-1 and sn-3 position. The molecular structure is well known from general literature on lipid chemistry.
https://stagingapi.mims.com/au/public/v2/images/fullchemgif/CSSOYAOI.gif Molecular weight: 871 g/mol (typical mean value, the molecular weight depends on the fatty acid pattern of the triglyceride).
CAS number. Active Substance: Soya oil.
CAS number: 8001-22-7.

7 Medicine Schedule (Poisons Standard)

Australia: Not Scheduled.
New Zealand: General Sale Medicine.

Summary Table of Changes

https://stagingapi.mims.com/au/public/v2/images/fulltablegif/INTRALST.gif